Polymersomes in “Gelly” Polymersomes: Toward Structural Cell Mimicry
نویسندگان
چکیده
منابع مشابه
Polymersomes.
Polymersomes are self-assembled polymer shells composed of block copolymer amphiphiles. These synthetic amphiphiles have amphiphilicity similar to lipids, but they have much larger molecular weights, so for this reason--along with others reviewed here--comparisons of polymersomes with viral capsids composed of large polypeptide chains are highly appropriate. We summarize the wide range of polym...
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Polymer vesicles polymersomes are vesicles obtained from the self-assembly of amphiphilic block copolymers in aqueous solution as a result of free-energy minimization. Their potential use as drug delivery systems, sensors, and/or nanoreactors has recently attracted a great deal of interest. Polymersomes exhibit larger mechanical stability and lower permeability than liposomes, their structural ...
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The ability of chelated Gd to serve as an effective magnetic resonance (MR) contrast agent largely depends on fast exchange rates between the Gd-bound water molecules and the surrounding bulk water. Because water diffuses slowly across lipid bilayers, liposomes with encapsulated chelated Gd have not been widely adopted as MR contrast agents. To overcome this limitation, we have synthesized chem...
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Enzyme-filled polystyrene-b-poly(3-(isocyano-L-alanyl-aminoethyl)thiophene) (PS-b-PIAT) nanoreactors are encapsulated together with free enzymes and substrates in a larger polybutadiene-b-poly(ethylene oxide) (PB-b-PEO) polymersome, forming a multicompartmentalized structure, which shows structural resemblance to the cell and its organelles. An original cofactor-dependent three-enzyme cascade r...
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Nanjing University of Chinese Medicine, Information Institute, 155 Hanzhong Rd, Bai Xia Qu, Nanjing, Jiangsu China; Xuzhou Central Hospital, Xuzhou 221009, Jiangsu Province, China; The Affiliated XuZhou Hospital of Medical College of Southeast University, Xuzhou, Jiangsu Province, China; Xuzhou Clinical School of Xuzhou Medical College, Xuzhou, Jiangsu Province, China; Xuzhou Clinical Medical C...
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ژورنال
عنوان ژورنال: Langmuir
سال: 2011
ISSN: 0743-7463,1520-5827
DOI: 10.1021/la204018w